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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTPRB All Species: 18.18
Human Site: T1900 Identified Species: 50
UniProt: P23467 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23467 NP_002828.3 1997 224328 T1900 R S P G A G P T V V H C S A G
Chimpanzee Pan troglodytes XP_509219 1996 223893 T1899 R S P G A G P T V V H C S A G
Rhesus Macaque Macaca mulatta XP_001117455 1997 224328 T1900 R S P G A G P T V V H C S A G
Dog Lupus familis XP_538283 2367 264000 T2118 R S P G A G P T V V H C S A G
Cat Felis silvestris
Mouse Mus musculus Q64455 1238 136750 G1143 I L V H C S A G V G R T G T F
Rat Rattus norvegicus Q64612 1711 187274 A1617 T L L T F L D A V G Q C C F R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512269 2148 240953 S2051 R T P G A G P S I V H C S A G
Chicken Gallus gallus Q9W6V5 1406 154195 V1312 L V H C S A G V G R T G T F I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P35992 1631 185062 P1537 G K E N I V G P A R E M H D N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 97 75.3 N.A. 24.8 20.6 N.A. 71.5 24.5 N.A. N.A. N.A. 25.9 N.A. N.A. N.A.
Protein Similarity: 100 97.8 98.4 79.8 N.A. 38.1 37.4 N.A. 81.4 40.5 N.A. N.A. N.A. 43.5 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 6.6 13.3 N.A. 80 0 N.A. N.A. N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 6.6 13.3 N.A. 100 13.3 N.A. N.A. N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 56 12 12 12 12 0 0 0 0 56 0 % A
% Cys: 0 0 0 12 12 0 0 0 0 0 0 67 12 0 0 % C
% Asp: 0 0 0 0 0 0 12 0 0 0 0 0 0 12 0 % D
% Glu: 0 0 12 0 0 0 0 0 0 0 12 0 0 0 0 % E
% Phe: 0 0 0 0 12 0 0 0 0 0 0 0 0 23 12 % F
% Gly: 12 0 0 56 0 56 23 12 12 23 0 12 12 0 56 % G
% His: 0 0 12 12 0 0 0 0 0 0 56 0 12 0 0 % H
% Ile: 12 0 0 0 12 0 0 0 12 0 0 0 0 0 12 % I
% Lys: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 12 23 12 0 0 12 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % M
% Asn: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 12 % N
% Pro: 0 0 56 0 0 0 56 12 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % Q
% Arg: 56 0 0 0 0 0 0 0 0 23 12 0 0 0 12 % R
% Ser: 0 45 0 0 12 12 0 12 0 0 0 0 56 0 0 % S
% Thr: 12 12 0 12 0 0 0 45 0 0 12 12 12 12 0 % T
% Val: 0 12 12 0 0 12 0 12 67 56 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _